Definitely! Megamind mispronounces words and his best friend struggles with spelling; that particular kind of smug ‘intellectual’ classism isn’t going to go down with him at all.
It’s interesting to me that, even though Megamind prides himself on his intellect, he never really uses it to make other people feel stupid.
He calls the people of Metrocity ‘mindless drones’, yes, but that seems to be based on them being so obsessed with Metro Man–he calls them ‘softheaded groupies’ first; his real complaint is with their blind worship of Metro Man.
When he thinks Minion doesn’t understand the definition of ‘melancholy’, he doesn’t mock Minion, but just phrases it different for him: “unhappy”.
He does the same thing for Hal, with the word ‘unfathomable’; when he says “you’ve been blessed with unfathomable powers!” and Hal says “what kind of powers?”, he starts to repeat the word ‘unfathomable’, then quickly and seamlessly changes to rephrasing it for Hal instead: “it’s without fathom”. And he does it without acting superior at all.